Sure enough, googling "coke up butt" took me right to this LiveLeak video having a young man blow a straw-full of cocaine into her anus.
mixing drugs—usually meth or cocaine—with water and squirting it into You might damage the tissue of the rectum and anus if you booty.
Rectal administration (aka plugging), has the second highest bioavailability (BA) of all routes of administration (ROA). The #1 highest BA is intravenous injection.
Am J Forensic Med Pathol. 1988 Dec;9(4):336-8. Investigation of a death caused by rectal insertion of cocaine. Doss PL(1), Gowitt GT. Author information.