Concerns around sodium valproate - does depakote affect sperm

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Reproductive toxicity of sodium valproate in male rats does depakote affect sperm


of the most frequently seen side effects affect the gastrointestinal, neurological, reproductive functions (hormonal levels and sperm parameters) will be presented , . ilepsy that did not use antiepileptic drugs than in healthy.

Results: As the VPA dose was increased, consecutive semen analyses were and that the VPA treatment did not cause permanent hormonal deregulation and, . that VPA directly affects sperm motility by inducing membrane stabilization.

To assess the effects of sodium valproate on rat sperm morphology, sperm count, . Sodium valproate did not alter the weight of the testes significantly. out that the germ cells affected are approximately the spermatids, spermatocytes, and.

7 Answers - Posted in: depakote, seizures, bipolar disorder, I could not find any info regarding men taking Depakote causing birth defects BUT I did Mutant sperm are not going to create a normal fetus I would have thought.